PRIME – GM 2 is a powerful combination therapy designed for Type 2 Diabetes Mellitus (T2DM) patients who require multi-targeted glucose control.
Glimepiride (2 mg) – A sulfonylurea that stimulates insulin secretion from pancreatic β-cells, effectively lowering blood sugar levels.
Pioglitazone (15 mg) – A thiazolidinedione (TZD) that enhances insulin sensitivity, allowing better glucose utilization by muscles and fat cells.
Metformin (500 mg SR) – A biguanide that reduces liver glucose production and improves insulin sensitivity while minimizing gastrointestinal side effects with its sustained-release (SR) formulation.
Available in: 10 X 10 Blister Pack
Why Choose PRIME – GM 2?
Triple Mechanism of Action – Enhances insulin secretion, improves insulin sensitivity, and reduces hepatic glucose production.
Better Glycemic Control – Helps maintain stable blood sugar levels throughout the day.
Reduces Insulin Resistance – Pioglitazone enhances insulin action, making it ideal for patients with metabolic syndrome.
Supports Cardiovascular Health – Helps reduce triglycerides & increase HDL (good cholesterol).
Sustained Release for Fewer Side Effects – Metformin SR formulation reduces gastric irritation & improves compliance.
Prevents Diabetes Complications – Reduces risk of neuropathy, nephropathy, & cardiovascular diseases.
Indications
Type 2 Diabetes Mellitus (T2DM) – For patients requiring multi-mechanism glucose control.
Uncontrolled Diabetes on Monotherapy – When Metformin or Glimepiride alone is insufficient.
Insulin Resistance & Metabolic Syndrome – Helps reduce insulin resistance and improve lipid profiles.
Long-Term Diabetes Management – Ideal for patients with progressive diabetes needing combination therapy.
Dosage & Administration
Recommended Dosage:
1 tablet once or twice daily, as prescribed by the physician.
Administration:
Take with meals to enhance effectiveness and reduce gastrointestinal side effects.
Swallow whole with water – Do not crush or chew.
Monitor blood sugar levels regularly to adjust dosage as needed.
Precautions & Warnings
Not for Type 1 Diabetes or Diabetic Ketoacidosis – Not suitable for insulin-dependent conditions.
Use with Caution in Kidney & Liver Disease – Dose adjustments may be necessary.
May Cause Hypoglycemia (Low Blood Sugar) – Symptoms include dizziness, sweating, tremors, & confusion.
Pioglitazone May Cause Fluid Retention – Avoid in patients with heart failure.
Metformin & Lactic Acidosis Risk – Monitor for symptoms like muscle pain, weakness, and difficulty breathing.
Avoid Excess Alcohol Intake – Increases risk of hypoglycemia & lactic acidosis.
Seek immediate medical attention if experiencing severe hypoglycemia, signs of fluid retention, or allergic reactions.
PRIME – GM 2 offers superior glycemic control through a triple-action approach, ensuring:
Reduced Blood Sugar Levels | Enhanced Insulin Sensitivity | Long-Term Diabetes Management
Comprehensive Solution for Type 2 Diabetes | Cardiovascular Benefits | Sustained-Release for Better Compliance
ACHIEVE BETTER DIABETES MANAGEMENT WITH PRIME – GM 2!
Note : Always Consult a physician before taking any medication, and do not rely solely on this information for medical advice.
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